Digital Health holds transformative potential for improving healthcare in low- and middle-income countries (LMICs) like Uganda, offering advancements in access, security, and cost-efficiency. However, Uganda's health system currently grapples with challenges such as fragmentation, duplication, lack of interoperability, and issues surrounding the security and privacy of health data. To comprehensively address these challenges, the p[Enterprise Architecture (EA) approach offers a systems-thinking approach to digitalization.

During his PhD research at Makerere University, Joseph Wamema, lead consultant at Value Informatics, developed a Digital Health Enterprise Architecture Framework (DHEAF) tailored to Uganda's health system. The framework uses the EA approach to standardise and enhance Digital Health practices nationwide. Crafted using TOGAF Version 9.2, the DHEAF aligns with the WHO-ITU eHealth model, which supports member states in creating standardised and interoperable national Digital Health ecosystems. This alignment ensures the framework meets global best practices while addressing local needs.

The framework's design and effectiveness were rigorously validated through stakeholder workshops. These workshops demonstrated a strong consensus among stakeholders that the DHEAF encompasses all essential components required to address Uganda's unique Digital Health needs. Furthermore, the framework was praised for its adaptability, user-friendliness, and capacity to standardise Digital Health interventions within Uganda's health system.

The study indicates that the DHEAF has significant potential to enhance the standardisation of Uganda's Digital Health ecosystem. Moreover, it presents a model that could be effectively utilised by other LMICs facing similar Digital Health challenges. This innovative approach by Value Informatics represents a crucial step forward in addressing digital health disparities and promoting more integrated, secure, and efficient healthcare systems globally.